Noise in Genetic Toggle Switch Models
نویسندگان
چکیده
In this paper we study the intrinsic noise effect on the switching behavior of a simple genetic circuit corresponding to the genetic toggle switch model. The numerical results obtained from a noisy mean-field model are compared to those obtained from the stochastic Gillespie simulation of the corresponding system of chemical reactions. Our results show that by using a two step reaction approach for modeling the transcription and translation processes one can make the system to lock in one of the steady states for exponentially long times.
منابع مشابه
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عنوان ژورنال:
- J. Integrative Bioinformatics
دوره 3 شماره
صفحات -
تاریخ انتشار 2006